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                       |---------|---------|---------|---------|---------|---------|---------|---------|---------|---------|---------|---------|---------|---------|---------|---------|---------|---------|---------|---------|---------|---------|---------|---------|---------|---------|---------|---------|---------|---------|---------|---------|---------|---------|---------|---------|---------|---------|---------|---------|---------|---------|---------|---------|---------|---------|---------|---------|---------|---------|---------|---------|---------|---------|---------|---------|---------|---------|---------|---------|---
 DYR_PNECA             --------------------MNQQKSLTLIVALTTSYGIGRSNSLPWK-LKKEISYFKRVTSFVPTFDSFESM--------------------------NVVLMGRKTWESIPLQFRPLKGRINVVITRNESLDLGNGIH-------------SAKSLDHALELLYRTYGSESSVQINRIFVIGGAQLYKAAMDHPKLDR---IMATIIYKDIHCDVFFPLKFRDKEWSSVWKKEKHSDLESWVGTKVPHGKINEDGFDYEFEMWTRDL  
 DYR_HSVSA             ----------------------MVQALNCIVAVAQNMGIGKQGNLPWPRLMNDFKHFQRMTTTSSVPDKQ-----------------------------NLVIMGKKTWFSIPEKNRPLKGRINVVLSKELKELPHRAHF----------------LAKSLDDALKLTEQPELANKVDMVWIIGGSSVYKEAMSYPCDLK---LFVTRIMQDFECDTFFPEFDLEKYKLLIEYPSVLSNVQEEKSIKYKFEVYEKNH  
 NRL_3DFR              --------------------------TAFLWAQNRNGLIGKDGHLPWH-LPDDLHYFRAQTVGK------------------------------------IMVVGRRTYESFPKRPLPERT--NVVLTHQEDYQAQ---------------------GAVVVHDVAAVFAYAKQHLDQELVIAGGAQIFTAFKDDVDT-----LLVTRLAGSFEGDTKMIPLNWDDFTKVSSRTVEDTNPALTHTYEVWQKKA  
 DYRB_ECOLI            ------------------------MKLSLMVAISKNGVIGNGPDIPWS-AKGEQLLFKAITYNQW------------------------------------LLVGRKTFESMGAL----PNRKYAVVTRSSFTSDNENVLIFPSI---------------------KDALTNLKKITDHVIVSGGGEIYKSLIDQVDT-----LHISTIDIEPEGDVYFPEIPSNFRPVFTQDFASNINYSYQIWQKG  
 DRTS_PLACH            --MEDISEIFDIYAICACCKVLNSNEKAGCFSNKTFKGLGNEGGLPWKCNSVDMKHFSSVTSYVNETNYMRLKWKRDRYMEKNNVKLNTDGIPSVDKLQNIVVMGKASWESIPSKFKPLQNRINIILSRTLKKEDLAKEY----------------NNVIIINSVDDLFPILKCIKYYKCFIIGGASVYKEFLDRNLIKK---IYFTRINNAYTCDVLFPDINEDLFKITSISDVYSSNNTTLDFVIYSKTKEIHEEINPNDELFNNTFLGVCDEKNTNFDDEDDYTYFSFNKHKDNIKKNSEHAHHFKIYNSIKYKHHPEYQYLNIIYDIIMHGNKQDDRTGVGVLSKFGYMMKFNLSEYFPLLTTKKLFVRGIIEELLWFIRGETNGNTLLEKNVRIWEANGTREFLDNRKLFHREVNDLGPIYGFQWRHFGAEYTDMHADYKDKGVDQLKNIINLIKNDPTCRRIILCAWNVKDLDQMALPPCHILCQFYVFDGKLSCIMYQRSCDLGLGVPFNIASYSIFTYMIAQVCNLQPAEFIHVLGNAHVYNNHVESLKVQLNRTPYPFPTLKLNPEIKNIEDFTISDFTVQNYVHHDKISMDMAA  
 DYR_YEAST             ------------------MAGGKIPIVGIVACLQPEMGIGFRGGVPWR-LPSEMKYFRQVTSLTKDPNKK-----------------------------NALIMGRKTWESIPPKFRPLPNRMNVIISRSFKDDFVHDKERSIVQSNS-------------LANAIMNLESNFKEHLERIYVIGGGEVYSQIFSITDH-----WLITKINPLDKNATPAMDTFLDAKKLEEVFSEQDPAQLKEFLPPKVELPETDCDQRYSLEEKGYCFEFTLYNRK  
 DRTS_LEIAM            MSRAAAKFKIPMPVTKADFAFPSLRAFSIVVALDKQHGIGDGESIPWR-VPEDMAFFKDQTTLLRNKKPPTDKKR------------------------NAVVMGRKTWESVPVKFRPLKGRLNVVLSSKATVEELLAPLPEEKRAAAAQ--DIVVVNGGLAAAVRLLARPPYCSSIETAYCVGGAQVYADAMLSPCVEKLQEVYLTRIHTTAPACTRFFPFPPENAATAWDLASSQ---GRRKSAVDGLEFEICKYVPRNHEERQYLELIDRIMKTGIAKEDRTGVGTLSLFGAQMRFSLRDNRLPLLTTKRVFWRGVCEELLWFLRGETNAQLLADKDIHIWDGNGSREFLDSRGLTENTEMDLGPVYGFQWRHFGAEYRGLEANYDGEGVDQIKFIVETIKANPNDRRLLFTAWNPCALHKMALPPCHLLAQFYVNTEKSELSCMLYQRSCDMGLGVPFNIASYALLTILIAKATGLRPGELVHTLGDAHVYRSHIDALKAQLERVPHAFPTLVFKEERQFLEDYELMDMEVIDYVPHPPIKMEMAV  
 DYR_HUMAN             -----------------------VGSLNCIVAVSQNMGIGKNGDLPWPPLRNEFRYFQRMTTTSSVEGKQ-----------------------------NLVIMGKKTWFSIPEKNRPLKGRINLVLSRELKEPPQGAHF----------------LSRSLDDALKLTEQPELANKVDMVWIVGGSSVYKEAMNHPGHLK---LFVTRIMQDFESDTFFPEIDLEKYKLLPEYPGVLSDVQEEKGIKYKFEVYEKND  
 DYR_BPT4              -----------------MIKLVFRYSPTKTVDGFNELAFGLGDGLPWGRVKKDLQNFKARTEGT------------------------------------IMIMGAKTFQSLPTL---LPGRSHIVVCDLARDYPVTKDGDLAHFYITWEQYITYISGGEIQVSSPNAPFETMLDQNSKVSVIGGPALLYAALPYADE------VVVSRIVKRHRVNSTVQLDASFLDDISKREMVETHWYKIDEVTTLTESVYK  
 DYR_NEIGO             -----------------------MLKITIIAACAENLCIGAGNAMPWH-IPEDFAFFKVYTLGKP------------------------------------VIMGRKTWESLPVKPLPGRR--NIVISRQADYCAAGAETVA-----------------------SLEVALALCAGAEEAVIMGGAQIYGQAMPLATD-----LRITEVDLSVEGDAFFPEIDRTHWREAERTERRVSSKGVAYTFVHYLGK