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 HEXB_FELCA            -------------------------------------------------------------------------------------------------------------------------------------------------------------------MPLSVKTSPRLLHLSRDNFSIGYGPSSTAGPTCSLLQEAFRRYH-----------EYIFGFDKRQRRPAKPNS----------AI-ELQQLLVTVVLDSECDLFPNITSDESYTLLVKEPV---------AFLKANRVWGVLRGLETFSQL-IYQDSYGTFTVN-------ESDIIDSPRFPHRGILIDTARHFLPVKSILKTLDAMAFNKFNVLHWHIVDDQSFPYQSVTFPELSNKGSYS-----------------------LSHVYTPNDVHTVIEYARLRGIRVIPEFDSPGHT------------------QSWGKGQKDLLTPCYNEHKQSGTFG-----PINPILNSTYNFLSQFFKEVSMVFP-----DHFVHLGGDEVE---------------FQCWESNP----EIQGFMKQ--------KGFGK-DFRRLESFYLQKLLGIVSTVKKGS----IVWQEVFDD-----HVKLLPGTIVQVWKNQV---YTEELREVTAAGFPVILS--APWYLD-----------------WISYGQDWRNYYKV------------------DPLHFDG--SQEQKKLVIGGEACLWGEFV-DATNLTPRLWPRASAVGERLWSPEDITS----------VGNAYNRLTVHRCRMVRR--GISAEPLFTGYCDYEYKT--  
 CHB_VIBHA             MLKHSLIAASVITTLAGCSSLQSSEQQVVNSLADNLDIQYEVLTNHGANEGLACQDMGAEWASCNKVNMTLVNQGEAVDSKDWAIYFHSIRLILDVDNEQFKISRVTGDLHKLEPTDKFDGFAAGEEVVLPLVGEYWQLFETDFMPGAFVSAPNA-------EPKMIASLNTEDVASFVTGLEGNNL--KRTPDDNNVFANAVSRFEKNEDLATQ---DVSTTLLPTPMHVEAGKGKVDIADGIALPKDAFDATQFAAIQDRAEVVGVDVRGDLPVSITVVPADFTGELAKSGAYEMSIKGDGIVIKAFDQAGAFYAVQSIFGLVDSQNADSLPQLSIKDAPRFDYRGVMVDVARNFHSKDAILATLDQMAAYKMNKLHLHLTDDEGWRLEIPGLPELTEVGANRCFDTQEKSCLLPQLGSGPTTDNFGSGYFSKADYVEILKYAKARNIEVIPEIDMPAHARAAVVSMEARYDRLMEEGKEAEANEYRLMDPQDTSNVTTVQFYNKQ-SFINPCMESSTRFVDKVISEVAAMHQEAGAPLTTWHFGGDEAKNIKLGAGFQDVNAEDKVSWKGTIDLSKQDKPFAQSPQCQTLITDGTVS-DFAHLPSHFAEEVSKIVAEKGIPN---FQAWQDGLKYSDG-EKAFATENTRVNFWDVLYWG-GTSSVYEWSKKGYDVIVSNPDYVYMDMPYEVDPK-------ERGYYWATRATDTRKMFGFAPENMPQNAETSVDRDGNGFTG-KGEIEAKPFYGLSAQLWSETVRNDEQYEYMVFPRVLAAAQRAWHRADWENDYK--------VGVEYSQNSNLVDKASLNQDYNRFANVLGQRELAKLEKSGIDYRLPVPGAKVEDGKLAMNVQFPGVTLQYSLDGENWLTYADNARPNVTGEVFIRSVSATGEKVSRITSVK  
 HEXA_MOUSE            ----------------------------------------------------------------------------------------------------------------------------------MAGCRLWVSLLLAAALACLAT--------ALWPWPQYIQTYHRRYTLYPNNFQFRYHVSSAAQGGCVVLDEAFRRYR-----------NLLFGSGSWPRPSFSNKQ----------QT-LGKNILVVSVVTAECNEFPNLESVENYTLTINDDQ---------CLLASETVWGALRGLETFSQL-VWKSAEGTFFIN-------KTKIKDFPRFPHRGVLLDTSRHYLPLSSILDTLDVMAYNKFNVFHWHLVDDSSFPYESFTFPELTRKGSFNP----------------------VTHIYTAQDVKEVIEYARLRGIRVLAEFDTPGHT------------------LSWGPGAPGLLTPCYSGSHLSGTFG-----PVNPSLNSTYDFMSTLFLEISSVFP-----DFYLHLGGDEVD---------------FTCWKSNP----NIQAFMKK--------KGF-T-DFKQLESFYIQTLLDIVSDYDKGY----VVWQEVFDN-----KVKVRPDTIIQVWREEMPVEYMLEMQDITRAGFRALLS--APWYLN-----------------RVKYGPDWKDMYKV------------------EPLAFHG--TPEQKALVIGGEACMWGEYV-DSTNLVPRLWPRAGAVAERLWSSNLTTN----------IDFAFKRLSHFRCELVRR--GIQAQPISVGYCEQEFEQT--  
 HEXC_BOMMO            ----------------------------------------------------------------------------------------------MWLQAICIYTVFIIIGCGIPTAAEEHSLWRWTCENNRCTKIRNEPENKEPVLSLEACKMFCDDYGLLWPKP-TIETNLGNFLSKINMNTIDIQITKQGK-SDDLLTAAADRFK-----------TLVSSSVPKGFSAKAAG----------------KSVTVYLVNENPYIREFSLDMDESYELYISSTSSD----KVNATIRGNSFFGVRNGLETLSQLIVYDDIRNNLLIVR------DVTIKDRPVYPYRGILLDTARNFYSIDSIKRTIDAMAAVKLNTFHWHITDSQSFPLVLQKRPNLSKLGAYS-----------------------PTKVYTKQDIREVVEYGLERGVRVLPEFDAPAHV-----------------GEGWQDTG---LTVCFKAEPWTKFCVEPPCGQLNPTKEELYDYLEDIYVEMAEAFES----TDMFHMGGDEVS---------------ERCWNSSE----EIQNFMIQN------RWNLDKSSFLKLWNYFQKNAQDRAYKAFGKR-LPLILWTSTLTDYTHVEKFLDKDEYIIQVWTTGA----DPQIQGLLQKGYRLIMSNYDALYFDCGFGAWVG--------SGNNWCSPYIGGQKV------------------YGNSPAV-MALSYRDQILGGEVALWSEQS-DPATLDGRLWPRAAAFAERMWAEPSTAW----------QDAEHRML-HVRERLVRM--GIQAESLEPEWCYQNQGLCYG--  
 HEX1_ENTHI            -----------------------------------------------------------------------------------------------------------------------------------MSKINWLSIIS------------------IE-----VTMSYCINFLKSNFNHTISFPLQ--------QQTGLQDFK-----------VSLFKEIDLPRITPSVSS--------------VITDVVVELSSSNPMPKLQIGFDESYILEVTTNS---------ISIKAVTVYGARHAFETLLQL-IRISSNKFVISQ------LPIKISDAPRFKWRGLMVDPSRNPLSPLMFKRIIDTLASVKANVLHIHLSDAQTFVFESKKYPLLHQKGMYD-----------------------ESFVLTQSFLRELAQYGANRGVIVYGEIDTPAHT------------------ASWNLGYPGVVANCWDYIVSTSMRYGENVLSLNPANPNTFPIIDALMKELSDTFG-----TDYVHVGGDEVW---------------TSGWSKSKEYS-DIQKFMKS--------KGLN--SLTELEGYFNKYAQEQVIHNGKHP----VVWEEVFK------KGNADKNTIIQVWDDIR------LLQQVVNSGYKAIFS--AGFYLDKQMPLCNSYDSSTCVNTHSMWVWTNRDMYDN------------------DPVKSLS--SSEKEN-VLGGEGCSWGEST-DEQNFFDRVFQRYSAIAERLWSKESVVD----------KESHEVRANYLRCLDVRRDIMKGTGPLYHSFCQLPKKEKSN--  
 HEXA_HUMAN            ----------------------------------------------------------------------------------------------------------------------------------MTSSRLWFSLLLAAAFAGRAT--------ALWPWPQNFQTSDQRYVLYPNNFQFQYDVSSAAQPGCSVLDEAFQRYR-----------DLLFGSGSWPRPYLTGKR----------HT-LEKNVLVVSVVTPGCNQLPTLESVENYTLTINDDQ---------CLLLSETVWGALRGLETFSQL-VWKSAEGTFFIN-------KTEIEDFPRFPHRGLLLDTSRHYLPLSSILDTLDVMAYNKLNVFHWHLVDDPSFPYESFTFPELMRKGSYNP----------------------VTHIYTAQDVKEVIEYARLRGIRVLAEFDTPGHT------------------LSWGPGIPGLLTPCYSGSEPSGTFG-----PVNPSLNNTYEFMSTFFLEVSSVFP-----DFYLHLGGDEVD---------------FTCWKSNP----EIQDFMRK--------KGFGE-DFKQLESFYIQTLLDIVSSYGKGY----VVWQEVFDN-----KVKIQPDTIIQVWREDIPVNYMKELELVTKAGFRALLS--APWYLN-----------------RISYGPDWKDFYVV------------------EPLAFEG--TPEQKALVIGGEACMWGEYV-DNTNLVPRLWPRAGAVAERLWSNKLTSD----------LTFAYERLSHFRCELLRR--GVQAQPLNVGFCEQEFEQT--  
 HEX1_CANAL            ---------------------------------------------------------------------------------------------------------------------------------MVLDKMIIFHLLLWLCN------------VVVHAAKVEILPAPQSVTWENDTAIIINPRLLQANTSCPLLEDAFVRTV-----------SAIEKSKWHPFPIDDFNT----------ANGKNIKTSLVHIQVDDATVDLQLGVNESYTLKINTDG---------INIHAATTWGALHGLVSLQQLIIHTSEDKYVVPS-------SVTISDFPNFKHRGLMIDSGRNFLTVDSILEQIDIMALSKMNSLHWHLADSQSWPVALESYPHMI-KDAYS-----------------------NDEVYSKNDLKYIVDYARARGVRVIPEIDMPGHA-----------------RAGWKQVDP-TIVECADAFWTDAAVEPPP-GQLNIESEKTYEVISNVYNELSDIFI-----DDVFHVGNDELQ---------------EKCYSAQLSPNNTVTDLLKRY--LKKALPIFNK-VNHRKLTMWDDVLLSDVSADKIPSNITLQVWHEISGV-----KNLTSRGYDVVVSSSDFLYLDCGNAGWVTNDPRYVETP--ENVDFNTGQ--------------GGSWCGPYKSYQRI------------------YNFDFTANLTETEKNHVLGREAALWSEQV-DSTVLTTKIWPRTAALAELTWSGNKDSNGHHR------GYEFTQRILNFREYLVKL--GYGVSPLVPKYCLLNPHACDLYKNPPVY  
 HEXA_DICDI            ----------------------------------------------------------------------------------------------------------------------------------MIKKIILFFAVLIAIVIGQQP-------LNVVPYPQQVSIGTCVIPVAPGSILIESNIESAT------FSVSMDRYT-----------NLFFPFSN-ESEPSSN-----------------ESFLLSVTIYSD-DETLQLGIDESYSLSIEQGS---------YQLKATNIYGAMRGLETFKQLIVYNELENSYSIV-------CVSISDSPRYPWRGFMVDSARHYIPKNMILHMIDSLGFSKFNTLHWHMVDAVAFPVESTTYPDLT-KGAFS-----------------------PSATFSHDDIQEVVAYAKTYGIRVIPEFDIPGHA------------------AAWGIGYPELVATCPDYAANVNNI------PLDISNPATFTFIQNLFTEIAPLFI-----DNYFHTGGDELV---------------TGCWLEDP----AIANWMTK--------MGF---STTDAFQYFENNLDVTMKSINRTK----ITWNDPIDY-----GVQLNPETLVQVWSSGS------DLQGIVNSGYKALVS--FAWYLDKQNPDN---------NIHYEWQDTWQDFYAA------------------DPTNNIS--TNAEN--IIGGEATMWAEQI-NQVNWDVRVWPRAIGIAERLWSAQSVNS----------VSLALPRIGHFTCDLSRR--GIQSGPLFPDYCPMQDDLVFTMKPNTKLSKSEIKLILNK  
 HEXB_HUMAN            ---------------------------------------------------------------------------------------------------------MELCGLGLPRPPMLLALLLATLLAAMLALLTQVALVVQVAEAARAPSVSAKPGPALWPLPLSVKMTPNLLHLAPENFYISHSPNSTAGPSCTLLEEAFRRYH-----------GYIFGFYKWHHEPAEFQA----------KT-QVQQLLVSITLQSECDAFPNISSDESYTLLVKEPV---------AVLKANRVWGALRGLETFSQL-VYQDSYGTFTIN-------ESTIIDSPRFSHRGILIDTSRHYLPVKIILKTLDAMAFNKFNVLHWHIVDDQSFPYQSITFPELSNKGSYS-----------------------LSHVYTPNDVRMVIEYARLRGIRVLPEFDTPGHT------------------LSWGKGQKDLLTPCYSRQNKLDSFG-----PINPTLNTTYSFLTTFFKEISEVFP-----DQFIHLGGDEVE---------------FKCWESNP----KIQDFMRQ--------KGFGT-DFKKLESFYIQKVLDIIATINKGS----IVWQEVFDD-----KAKLAPGTIVEVWKDSA---YPEELSRVTASGFPVILS--APWYLD-----------------LISYGQDWRKYYKV------------------EPLDFGG--TQKQKQLFIGGEACLWGEYV-DATNLTPRLWPRASAVGERLWSSKDVRD----------MDDAYDRLTRHRCRMVER--GIAAQPLYAGYCNHENM--  
 HEX_VIBVU             -MASDIDQKDVDYAAKNLKLTTSLVANKPKD-----------------------CPPEAPWGACYRVEINLENTGSKSLNENVEIYFSSIHRTLGSKSEEFKVEHINGDLHKITTTEKFKGLKGGKTKSFQVDFMNWIVSNSDFMPNYYVASEHLEGRNILNTVPIDAVHITEEVSGFTTGIKHTPNQLKRTANDLLPAATATTRYEQYSKVKDLGADAVSAHILPTPLETSVHEGSLNIAQGINIVSDALPADQVEALNFRFETLGVNTGTGVPVNVTIKADSSK----KSGSYTLDVTSSGIRIVGVDKAGAFYGVQSLAGLVTVGK-DTINQVSINDEPRLDYRGMHMDVSRNFHSKELVFRFLDQMAAYKMNKFHFHLADDEGWRLEINGLPELTQVGAHRCHDVEQNKCMMPQLGSGAELPNNGSGYYTREDYKEILAYASARNIQVIPSMDMPGHSLAAVKSMEARYRKFMAEGDVVKAEMYLLSDPNDTTQYYSIQHYQDN--TINPCMESSFVFMDKVIDEINKLHKEGGQPLTDYHIGADETAG--------------AWGD--SPE---CRKMFVAP---------ESGVKNAKDINGYFINRISHILDAKGLTLG----AWNDGLSHKALDASSLAGNPPKAWVWGTMFWG-GVDQYNSFANKGYDVVVTPPDAYYFDMPYENDPE-------ERGYYWATRFNDTKKVFSFMPENVPANVEWMTDRMGAKISAT-TGEKTHDFLGVQGALWSETIRTDAQVEYMVLPRMIAVAERGWHKASWEEEHKEGITYTSNVDGHEGTTHLNDNIATRDADWAHFSNILGYKEMPKLDKAGITYRLPVLGAVIKNNILDVVTEFHGVAIQYSLDGKTWHKYDDTKKPQVSTKALVRSVSTNGRTGRAVEVLAK  
 HEXB_MOUSE            ---------------------------------------------------------------------------------------------------------------------------MPQSPRSAPGLLLLQALVSLVSLALVAP---ARLQPALWPFPRSVQMFPRLLYISAEDFSIDHSPNSTAGPSCSLLQEAFRRYY-----------NYVFGFYKRHHGPARFRA----------EP-QLQKLLVSITLESECESFPSLSSDETYSLLVQEPV---------AVLKANSVWGALRGLETFSQL-VYQDSFGTFTIN-------ESSIADSPRFPHRGILIDTSRHFLPVKTILKTLDAMAFNKFNVLHWHIVDDQSFPYQSTTFPELSNKGSYS-----------------------LSHVYTPNDVRMVLEYARLRGIRVIPEFDTPGHT------------------QSWGKGQKNLLTPCYNQKTKTQVFG-----PVDPTVNTTYAFFNTFFKEISSVFP-----DQFIHLGGDEVE---------------FQCWASNP----NIQGFMKR--------KGFGS-DFRRLESFYIKKILEIISSLKKNS----IVWQEVFDD-----KVELQPGTVVEVWKSEH---YSYELKQVTGSGFPAILS--APWYLD-----------------LISYGQDWKNYYKV------------------EPLNFEG--SEKQKQLVIGGEACLWGEFV-DATNLTPRLWPRASAVGERLWSPKTVTD----------LENAYKRLAVHRCRMVSR--GIAAQPLYTGYCNYENKI--