WORKLIST ENTRIES (1):

ETSDOMAIN View alignment View Structure       ETS domain signature
 Type of fingerprint: COMPOUND with 4  elements
Links:
   PROSITE; PS00345 ETS_DOMAIN_1; PS00346 ETS_DOMAIN_2
   PFAM; PF00178 Ets
   SMART; SM00413 ETS
   INTERPRO; IPR000418
   PDB; 2STT 3Dinfo
   SCOP; 2STT
   CATH; 2STT

 Creation date 15-FEB-1996; UPDATE 19-AUG-2001

   1. GUNTHER, C.V., NYE, J.A., BRYNER, R.S. AND GRAVES, B.J.
   Sequence-specific DNA binding of the proto-oncoprotein ets-1 defines a 
   transcriptional activator sequence within the long terminal repeat of the 
   Moloney murine sarcoma virus.
   GENES DEV. 4 667-679 (1990).

   2. KARIM, F.D., URNESS, L.D., THUMMEL, C.S., KLEMSZ, M.J., MCKERCHER, S.R.,
   CELADA, A., VAN BEVEREN, C., MAKI, R.A., GUNTHER, C.V., NYE, J.A. AND 
   GRAVES, B.J.
   The ETS-domain: a new DNA-binding motif that recognizes a purine-rich core
   DNA sequence.
   GENES DEV. 4 1451-1453 (1990).

   3. WASYLYK, B., HAHN, S.L. AND GIOVANE, A.
   The Ets family of transcription factors.
   EUR.J.BIOCHEM. 211 7-18 (1993).

   4. WERNER, M.H., CLORE, G.M., FISHER, C.L., FISHER, R.J., TRINH, L.,
   SHILOACH, J. AND GRONENBORN, A.M.
   The solution structure of the human ETS1-DNA complex reveals a novel
   mode of binding and true side chain intercalation.
   CELL 83 761-771 (1995).

   Transcription factors are protein molecules that bind to specific DNA
   sequences in the genome, resulting in the induction or inhibition of gene
   transcription [1]. The ets oncogene is such a factor, possessing a region 
   of 85-90 amino acids known as the ETS domain [1,2]. This domain is rich in
   positively-charged and aromatic residues, and binds to purine-rich segments
   of DNA. The ETS domain has been idenitified in other transcription factors
   such as PU.1, human erg, human elf-1, human elk-1, GA binding protein, and
   a number of others [1-3].
   
   The solution structure of a specific human ETS1-DNA complex has been solved
   by NMR [4]. The protein-DNA interaction reveals a twist on the general
   features of helix-turn-helix (HTH)-DNA interactions. Major groove
   recognition involves the C-terminal two-thirds of the HTH recognition helix,
   while minor groove recognition occurs via intercalation of the side chain of 
   Trp-28, which extends from the minor to the major groove [4]. This results
   in a kink of ~60 degrees and a widening of the minor groove. These
   observations establish the ETS family of DNA-binding proteins as a distinct
   family of HTH proteins [4].
  
   ETSDOMAIN is a 4-element fingerprint that provides a signature for the 
   ETS DNA-binding domain. The fingerprint was derived from an initial
   alignment of 7 sequences: the motifs were drawn from conserved regions
   spanning virtually the full domain length - motif 1 encodes alpha-helix 2;
   motif 2 spans beta-strand 2 and helix 4; motif 3 encodes helix 5; and motif
   4 spans strands 3 and 4. Two iterations on OWL27.0 were required to reach
   convergence, at which point a true set comprising 70 sequences was 
   identified. Five partial matches were also found, all of which are related
   proteins that fail to make significant matches with one or more motifs.
  
   An update on SPTR39.22_17.3f identified a true set of 125 sequences, and
   again 5 partial matches.

  SUMMARY INFORMATION
    125 codes involving  4 elements
      3 codes involving  3 elements
      2 codes involving  2 elements

   COMPOSITE FINGERPRINT INDEX
  
    4| 125  125  125  125  
    3|   1    3    3    2  
    2|   0    2    2    0  
   --+---------------------
     |   1    2    3    4  

True positives..
 PNT1_DROME     PNT2_DROME     Q9VCN2         ET1A_XENLA     
 ETS1_HUMAN     ETS1_MOUSE     ETS1_RAT       ETSA_CHICK     
 ETSB_CHICK     Q26645         ET2A_XENLA     ETS2_HUMAN     
 ETS2_MOUSE     Q99K36         ET2B_XENLA     ETS3_DROME     
 ETS2_CHICK     Q9BZD1         Q9W700         Q9W6Z9         
 Q9PU61         O93425         FLI1_MOUSE     FLI1_HUMAN     
 ERG_HUMAN      ERG_CHICK      O70132         Q99581         
 Q18579         Q22355         FLI1_XENLA     ETS6_DROME     
 O57566         Q9PU63         ELK4_MOUSE     Q9I9E8         
 GABA_MOUSE     GABA_HUMAN     Q98SI4         ETV4_MOUSE     
 ELK3_HUMAN     ELK1_HUMAN     ELK1_MOUSE     ETV1_HUMAN     
 ETV1_MOUSE     Q9W696         Q9YHW6         O57586         
 ELK4_HUMAN     ELK3_MOUSE     Q9PUQ1         ERM_HUMAN      
 Q9CXC9         Q9JHB1         Q9PUQ2         ELF1_HUMAN     
 ELF1_MOUSE     Q9EQY1         Q9EQY2         Q9EQY3         
 Q27378         Q9YH25         ELG_DROME      Q9VC38         
 Q9Z2U4         Q99607         O60435         Q15723         
 Q15724         Q15725         Q9JHC7         Q9JHC8         
 Q9JHC9         Q9JHD0         Q9YH24         Q9YHU5         
 E74A_DROME     E74B_DROME     O17057         Q9BX30         
 Q9QZW1         ETV2_MOUSE     ERF_HUMAN      ERF_MOUSE      
 ETV2_HUMAN     POK_DROME      O96416         O97145         
 O70273         Q99K12         Q9H509         Q9NZC4         
 Q9UKF9         Q9Y5V4         Q9Y5V5         O95238         
 Q9WTP3         P78545         O35275         Q99718         
 ETS4_DROME     O95175         Q9Z2K6         Q9UKW6         
 Q9UKW5         O42415         PU1_HUMAN      PU1_MOUSE      
 Q99L57         Q9I8M7         ETV6_MOUSE     ETV6_HUMAN     
 Q19695         Q9I8M4         TEL2_HUMAN     Q9DEW6         
 O01521         O97553         SPIB_HUMAN     Q9I8M6         
 Q9DEW5         Q9I8M5         Q9I8M8         Q9DEW4         
 P93750         
Subfamily:  Codes involving 3 elements
 Subfamily True positives..
 O01519         O44138         Q9Z0Y0         
Subfamily:  Codes involving 2 elements
 Subfamily True positives..
 Q93320         Q22941         


  PROTEIN TITLES
   PNT1_DROME       ETS-LIKE PROTEIN POINTED P1 (D-ETS-2) - Drosophila melanogas
   PNT2_DROME       ETS-LIKE PROTEIN POINTED P2 (D-ETS-2) - Drosophila melanogas
   Q9VCN2           PNT PROTEIN - Drosophila melanogaster (Fruit fly).
   ET1A_XENLA       C-ETS-1A PROTEIN - Xenopus laevis (African clawed frog).
   ETS1_HUMAN       C-ETS-1 PROTEIN (P54) - Homo sapiens (Human).
   ETS1_MOUSE       C-ETS-1 PROTEIN (P54) - Mus musculus (Mouse).
   ETS1_RAT         C-ETS-1 PROTEIN (P54) - Rattus norvegicus (Rat).
   ETSA_CHICK       TRANSFORMING PROTEIN P54/C-ETS-1 - Gallus gallus (Chicken).
   ETSB_CHICK       TRANSFORMING PROTEIN P68/C-ETS-1 - Gallus gallus (Chicken).
   Q26645           ETS HOMOLOGUE - Strongylocentrotus purpuratus (Purple sea ur
   ET2A_XENLA       C-ETS-2A PROTEIN - Xenopus laevis (African clawed frog).
   ETS2_HUMAN       C-ETS-2 PROTEIN - Homo sapiens (Human).
   ETS2_MOUSE       C-ETS-2 PROTEIN - Mus musculus (Mouse).
   Q99K36           E26 AVIAN LEUKEMIA ONCOGENE 2, 3' DOMAIN - Mus musculus (Mou
   ET2B_XENLA       C-ETS-2B PROTEIN - Xenopus laevis (African clawed frog).
   ETS3_DROME       DNA-BINDING PROTEIN D-ETS-3 - Drosophila melanogaster (Fruit
   ETS2_CHICK       C-ETS-2 PROTEIN - Gallus gallus (Chicken).
   Q9BZD1           EWINGS SARCOMA EWS-FLI1 (TYPE 1) ONCOGENE - Homo sapiens (Hu
   Q9W700           ERG PROTEIN - Xenopus laevis (African clawed frog).
   Q9W6Z9           ERG PROTEIN - Xenopus laevis (African clawed frog).
   Q9PU61           FLI-1 PROTEIN - Brachydanio rerio (Zebrafish) (Zebra danio).
   O93425           FLI TRANSCRIPTION FACTOR - Coturnix coturnix japonica (Japan
   FLI1_MOUSE       RETROVIRAL INTEGRATION SITE PROTEIN FLI-1 - Mus musculus (Mo
   FLI1_HUMAN       FLI-1 ONCOGENE (ERGB TRANSCRIPTION FACTOR) - Homo sapiens (H
   ERG_HUMAN        TRANSCRIPTIONAL REGULATOR ERG (TRANSFORMING PROTEIN ERG) - H
   ERG_CHICK        TRANSCRIPTIONAL REGULATOR ERG - Gallus gallus (Chicken).
   O70132           ETS DOMAIN TRANSCRIPTION FACTOR PET-1 - Rattus norvegicus (R
   Q99581           FEV PROTEIN - Homo sapiens (Human).
   Q18579           SIMILARITY TO ETS DOMAINS - Caenorhabditis elegans.
   Q22355           T08H4.3 PROTEIN - Caenorhabditis elegans.
   FLI1_XENLA       RETROVIRAL INTEGRATION SITE PROTEIN FLI-1 HOMOLOG - Xenopus 
   ETS6_DROME       DNA-BINDING PROTEIN D-ETS-6 - Drosophila melanogaster (Fruit
   O57566           TRANSCRIPTION FACTOR GETS-1 - Carassius auratus (Goldfish).
   Q9PU63           TCF-1 PROTEIN - Brachydanio rerio (Zebrafish) (Zebra danio).
   ELK4_MOUSE       ETS-DOMAIN PROTEIN ELK-4 (SERUM RESPONSE FACTOR ACCESSORY PR
   Q9I9E8           E4TF1-60 TRANSCRIPTION FACTOR - Brachydanio rerio (Zebrafish
   GABA_MOUSE       GA BINDING PROTEIN ALPHA CHAIN (GABP-ALPHA SUBUNIT) - Mus mu
   GABA_HUMAN       GA BINDING PROTEIN ALPHA CHAIN (GABP-ALPHA SUBUNIT) (TRANSCR
   Q98SI4           TERNARY COMPLEX FACTOR XSAP1 - Xenopus laevis (African clawe
   ETV4_MOUSE       POLYOMAVIRUS ENHANCER ACTIVATOR 3 (PEA3 PROTEIN) (ETS TRANSL
   ELK3_HUMAN       ETS-DOMAIN PROTEIN ELK-3 (ETS-RELATED PROTEIN NET) (ETS-RELA
   ELK1_HUMAN       ETS-DOMAIN PROTEIN ELK-1 - Homo sapiens (Human).
   ELK1_MOUSE       ETS-DOMAIN PROTEIN ELK-1 - Mus musculus (Mouse).
   ETV1_HUMAN       ETS TRANSLOCATION VARIANT 1 (ER81 PROTEIN) - Homo sapiens (H
   ETV1_MOUSE       ER81 PROTEIN (ETS TRANSLOCATION VARIANT 1) - Mus musculus (M
   Q9W696           ETS TRANSCRIPTION FACTOR - Xenopus laevis (African clawed fr
   Q9YHW6           ETS DOMAIN PROTEIN - Gallus gallus (Chicken).
   O57586           ETS-DOMAIN TRANSCRIPTION FACTOR PEA3 - Brachydanio rerio (Ze
   ELK4_HUMAN       ETS-DOMAIN PROTEIN ELK-4 (SERUM RESPONSE FACTOR ACCESSORY PR
   ELK3_MOUSE       ETS-DOMAIN PROTEIN ELK-3 (ETS-RELATED PROTEIN NET) (ETS-RELA
   Q9PUQ1           PEA3 - Brachydanio rerio (Zebrafish) (Zebra danio).
   ERM_HUMAN        ETS-RELATED PROTEIN ERM (ETS TRANSLOCATION VARIANT 5) - Homo
   Q9CXC9           8430401F14RIK PROTEIN - Mus musculus (Mouse).
   Q9JHB1           ETS-RELATED TRANSCRIPTION FACTOR - Mus musculus (Mouse).
   Q9PUQ2           ETS RELATED PROTEIN ERM - Brachydanio rerio (Zebrafish) (Zeb
   ELF1_HUMAN       ETS-RELATED TRANSCRIPTION FACTOR ELF-1 (E74-LIKE FACTOR 1) -
   ELF1_MOUSE       ETS-RELATED TRANSCRIPTION FACTOR ELF-1 (E74-LIKE FACTOR 1) -
   Q9EQY1           TRANSCRIPTION FACTOR ELF-1 - Rattus norvegicus (Rat).
   Q9EQY2           TRANSCRIPTION FACTOR ELF-1 - Rattus norvegicus (Rat).
   Q9EQY3           TRANSCRIPTION FACTOR ELF-1 - Rattus norvegicus (Rat).
   Q27378           TRANSCRIPTION FACTOR LIN-1 - Caenorhabditis elegans.
   Q9YH25           E74-LIKE FACTOR-1 - Brachydanio rerio (Zebrafish) (Zebra dan
   ELG_DROME        DNA-BINDING PROTEIN D-ELG - Drosophila melanogaster (Fruit f
   Q9VC38           CG6892 PROTEIN - Drosophila melanogaster (Fruit fly).
   Q9Z2U4           MYELOID ELF-1-LIKE FACTOR - Mus musculus (Mouse).
   Q99607           MYELOID ELF-1 LIKE FACTOR - Homo sapiens (Human).
   O60435           ELF-1 RELATED PROTEIN - Homo sapiens (Human).
   Q15723           ETS TRANSCRIPTION FACTOR (ETS FAMILY TRANSCRIPTION FACTOR EL
   Q15724           NERF-1B - Homo sapiens (Human).
   Q15725           NERF-1A (ETS FAMILY TRANSCRIPTION FACTOR ELF2B) - Homo sapie
   Q9JHC7           ETS FAMILY TRANSCRIPTION FACTOR ELF2B2 - Mus musculus (Mouse
   Q9JHC8           ETS FAMILY TRANSCRIPTION FACTOR ELF2B1 - Mus musculus (Mouse
   Q9JHC9           ETS FAMILY TRANSCRIPTION FACTOR ELF2A2 - Mus musculus (Mouse
   Q9JHD0           ETS FAMILY TRANSCRIPTION FACTOR ELF2A1 - Mus musculus (Mouse
   Q9YH24           E74-LIKE FACTOR-2 - Brachydanio rerio (Zebrafish) (Zebra dan
   Q9YHU5           TRANSCRIPTION FACTOR E4TF1 - Fugu rubripes (Japanese pufferf
   E74A_DROME       ECDYSONE-INDUCED PROTEIN 74EFA (ETS-RELATED PROTEIN E74A) - 
   E74B_DROME       ECDYSONE-INDUCED PROTEIN 74EFB (ETS-RELATED PROTEIN E74B) - 
   O17057           C24A1.2 PROTEIN - Caenorhabditis elegans.
   Q9BX30           BA110J1.4 (ETS VARIANT 3) - Homo sapiens (Human).
   Q9QZW1           ETS-DOMAIN TRANSCRIPTIONAL REPRESSOR PE1 - Mus musculus (Mou
   ETV2_MOUSE       ETS TRANSLOCATION VARIANT 2 (ETS-RELATED PROTEIN 71) - Mus m
   ERF_HUMAN        ETS-DOMAIN TRANSCRIPTION FACTOR ERF (ETS2 REPRESSOR FACTOR) 
   ERF_MOUSE        ETS-DOMAIN TRANSCRIPTION FACTOR ERF - Mus musculus (Mouse).
   ETV2_HUMAN       ETS TRANSLOCATION VARIANT 2 (ETS-RELATED PROTEIN 71) - Homo 
   POK_DROME        ETS DNA-BINDING PROTEIN POKKURI (PROTEIN YAN) (PROTEIN ANTER
   O96416           ETS DNA BINDING PROTEIN YAN - Drosophila virilis (Fruit fly)
   O97145           ETS4 TRANSCRIPTION FACTOR - Strongylocentrotus purpuratus (P
   O70273           ETS HOMOLOGOUS FACTOR (EHF) (EHF) - Mus musculus (Mouse).
   Q99K12           SIMILAR TO ETS HOMOLOGOUS FACTOR - Mus musculus (Mouse).
   Q9H509           DJ875K15.1.1 (ETS HOMOLOGOUS FACTOR (ETS-DOMAIN TRANSCRIPTIO
   Q9NZC4           ETS DOMAIN TRANSCRIPTION FACTOR (DJ875K15.1.2) - Homo sapien
   Q9UKF9           ETS HOMOLOGOUS FACTOR - Homo sapiens (Human).
   Q9Y5V4           TRANSCRIPTION FACTOR ESE-3B - Homo sapiens (Human).
   Q9Y5V5           TRANSCRIPTION FACTOR ESE-3A - Homo sapiens (Human).
   O95238           ETS TRANSCRIPTION FACTOR PDEF (PROSTATE ETS) - Homo sapiens 
   Q9WTP3           PROSTATE SPECIFIC TRANSCRIPTION FACTOR ETS - Mus musculus (M
   P78545           ESE-1B (E74-LIKE FACTOR 3) (ETS DOMAIN TRANSCRIPTION FACTOR,
   O35275           E74-LIKE FACTOR 3 (ETS TRANSCRIPTION FACTOR) - Mus musculus 
   Q99718           EPITHELIAL-SPECIFIC TRANSCRIPTION FACTOR ESE-1A - Homo sapie
   ETS4_DROME       DNA-BINDING PROTEIN D-ETS-4 - Drosophila melanogaster (Fruit
   O95175           E74-LIKE FACTOR 5 - Homo sapiens (Human).
   Q9Z2K6           E74-LIKE FACTOR 5 - Mus musculus (Mouse).
   Q9UKW6           ETS TRANSCRIPTION FACTOR ESE-2A - Homo sapiens (Human).
   Q9UKW5           ETS TRANSCRIPTION FACTOR ESE-2B - Homo sapiens (Human).
   O42415           SPI-1/PU.1 TRANSCRIPTION FACTOR - Gallus gallus (Chicken).
   PU1_HUMAN        31 KDA TRANSFORMING PROTEIN (TRANSCRIPTION FACTOR PU.1) - Ho
   PU1_MOUSE        31 KDA TRANSFORMING PROTEIN (TRANSCRIPTION FACTOR PU.1) - Mu
   Q99L57           SFFV PROVIRAL INTEGRATION 1 - Mus musculus (Mouse).
   Q9I8M7           SPI-1/PU.1 TRANSCRIPTION FACTOR - Paleosuchus palpebrosus (C
   ETV6_MOUSE       TRANSCRIPTION FACTOR ETV6 (ETS-RELATED PROTEIN TEL1) (TEL) (
   ETV6_HUMAN       TRANSCRIPTION FACTOR ETV6 (ETS-RELATED PROTEIN TEL1) (TEL) (
   Q19695           SIMILAR TO DNA BINDING PROTEIN - Caenorhabditis elegans.
   Q9I8M4           SPI-1/PU.1 TRANSCRIPTION FACTOR - Aulonocara hansbaenschi.
   TEL2_HUMAN       TRANSCRIPTION FACTOR TEL-2 (ETS-RELATED PROTEIN TEL2) (TEL R
   Q9DEW6           PU.1 - Raja eglanteria.
   O01521           SIMILARITY TP THE DNA-BINDING DOMAIN OF ETS FAMILY OF PROTEI
   O97553           B42B - Cercopithecus aethiops (Green monkey) (Grivet).
   SPIB_HUMAN       TRANSCRIPTION FACTOR SPI-B - Homo sapiens (Human).
   Q9I8M6           SPI-B TRANSCRIPTION FACTOR - Paleosuchus palpebrosus (Cuvier
   Q9DEW5           SPID - Raja eglanteria.
   Q9I8M5           SPI-B TRANSCRIPTION FACTOR - Xenopus laevis (African clawed 
   Q9I8M8           SPI TRANSCRIPTION FACTOR - Petromyzon marinus (Sea lamprey).
   Q9DEW4           SPIC - Raja eglanteria.
   P93750           HYPOTHETICAL 137.9 KDA PROTEIN - Arabidopsis thaliana (Mouse
 
   O01519           SIMILARITY TO THE DNA-BINDING DOMAIN OF THE ETS FAMILY OF PR
   O44138           C50A2.4 PROTEIN - Caenorhabditis elegans.
   Q9Z0Y0           ETS-PROTEIN SPI-C - Mus musculus (Mouse).
 
   Q93320           C33A11.4 PROTEIN - Caenorhabditis elegans.
   Q22941           C52B9.2 PROTEIN - Caenorhabditis elegans.

SCAN HISTORY OWL27_0 2 100 NSINGLE SPTR37_9f 4 200 NSINGLE SPTR39.22_17.3f 6 220 NSINGLE INITIAL MOTIF SETS ETSDOMAIN1 Length of motif = 14 Motif number = 1 ETS domain motif I - 1 PCODE ST INT IQLWQFLLELLTDK ETS1_MOUSE 335 335 IQLWQFLLELLTDK ETS1_HUMAN 335 335 IQLWQFLLELLTDK ETSB_CHICK 379 379 IQLWQFLLELLTDK ETS2_CHICK 373 373 IYLWEFLLALLQDK ELF1_HUMAN 208 208 IQLWQFLLELLADS ETS6_DROME 255 255 VTLWQFLLQLLREQ ELK1_MOUSE 5 5 ETSDOMAIN2 Length of motif = 19 Motif number = 2 ETS domain motif II - 1 PCODE ST INT DGWEFKLSDPDEVARRWGK ETS1_MOUSE 359 10 DGWEFKLSDPDEVARRWGK ETS1_HUMAN 359 10 DGWEFKLSDPDEVARRWGK ETSB_CHICK 403 10 DGWEFKLADPDEVARRWGR ETS2_CHICK 397 10 EKGIFKLVDSKAVSRLWGK ELF1_HUMAN 234 12 QSGEFRLIDPDEVARRWGE ETS6_DROME 279 10 DGGEFKLVDAEEVARLWGL ELK1_MOUSE 30 11 ETSDOMAIN3 Length of motif = 19 Motif number = 3 ETS domain motif III - 1 PCODE ST INT RKNKPKMNYEKLSRGLRYY ETS1_MOUSE 378 0 RKNKPKMNYEKLSRGLRYY ETS1_HUMAN 378 0 RKNKPKMNYEKLSRGLRYY ETSB_CHICK 422 0 RKNKPKMNYEKLSRGLRYY ETS2_CHICK 416 0 HKNKPDMNYETMGRALRYY ELF1_HUMAN 253 0 RKAKPNMNYDKLSRALRYY ETS6_DROME 298 0 RKNKTNMNYDKLSRALRYY ELK1_MOUSE 49 0 ETSDOMAIN4 Length of motif = 19 Motif number = 4 ETS domain motif IV - 1 PCODE ST INT YDKNIIHKTAGKRYVYRFV ETS1_MOUSE 397 0 YDKNIIHKTAGKRYVYRFV ETS1_HUMAN 397 0 YDKNIIHKTAGKRYVYRFV ETSB_CHICK 441 0 YDKNIIHKTSGKRYVYRFV ETS2_CHICK 435 0 YQRGILAKVEGQRLVYQFK ELF1_HUMAN 272 0 YDKNIMTKVHGKRYAYKFD ETS6_DROME 317 0 YDKNIIRKVSGQKFVYKFV ELK1_MOUSE 68 0 FINAL MOTIF SETS ETSDOMAIN1 Length of motif = 14 Motif number = 1 ETS domain motif I - 6 PCODE ST INT IQLWQFLLELLLDK PNT1_DROME 515 515 IQLWQFLLELLLDK PNT2_DROME 610 610 IQLWQFLLELLLDK Q9VCN2 610 610 IQLWQFLLELLTDK ET1A_XENLA 332 332 IQLWQFLLELLTDK ETS1_HUMAN 335 335 IQLWQFLLELLTDK ETS1_MOUSE 335 335 IQLWQFLLELLTDK ETS1_RAT 335 335 IQLWQFLLELLTDK ETSA_CHICK 335 335 IQLWQFLLELLTDK ETSB_CHICK 379 379 IQLWQFLLELLTDK Q26645 448 448 IQLWQFLLELLTDK ET2A_XENLA 366 366 IQLWQFLLELLSDK ETS2_HUMAN 363 363 IQLWQFLLELLSDK ETS2_MOUSE 362 362 IQLWQFLLELLSDK Q99K36 362 362 IQLWQFLLELLTDK ET2B_XENLA 366 366 IQLWQFLLELLSDS ETS3_DROME 11 11 IQLWQFLLELLTDK ETS2_CHICK 373 373 IQLWQFLLELLSDS Q9BZD1 305 305 IQLWQFLLELLSDS ERG_CHICK 310 310 IQLWQFLLELLSDS ERG_HUMAN 294 294 IQLWQFLLELLSDS FLI1_HUMAN 281 281 IQLWQFLLELLSDS FLI1_MOUSE 281 281 IQLWQFLLELLSDS O93425 261 261 IQLWQFLLELLSDS Q9PU61 280 280 IQLWQFLLELLSDS Q9W6Z9 288 288 IQLWQFLLELLSDS Q9W700 317 317 IQLWQFLLELLADR O70132 150 150 IQLWQFLLELLADR Q99581 47 47 IQLWQFLLELLADA Q18579 35 35 TQLWQFLLELLSDK Q22355 214 214 IQLWQFLLELLSDS FLI1_XENLA 282 282 IQLWQFLLELLADS ETS6_DROME 255 255 VTLWQFLLQLLLDP O57566 16 16 VTLWQFLLQLLLDP Q9PU63 5 5 ITLWQFLLQLLQEP ELK4_MOUSE 5 5 IQLWQFLLELLTDK Q9I9E8 310 310 IQLWQFLLELLTDK GABA_HUMAN 320 320 IQLWQFLLELLTDK GABA_MOUSE 320 320 ITLWQFLLQLLQEP Q98SI4 5 5 LQLWQFLVALLDDP ETV4_MOUSE 412 412 ITLWQFLLQLLLDQ ELK3_HUMAN 5 5 VTLWQFLLQLLREQ ELK1_HUMAN 5 5 VTLWQFLLQLLREQ ELK1_MOUSE 5 5 LQLWQFLVALLDDP ETV1_HUMAN 335 335 LQLWQFLVALLDDP ETV1_MOUSE 335 335 LQLWQFLVALLDDP Q9W696 335 335 LQLWQFLVALLDDP Q9YHW6 335 335 LQLWQFLVALLDDP O57586 350 350 ITLWQFLLQLLQKP ELK4_HUMAN 5 5 ITLWQFLLHLLLDQ ELK3_MOUSE 5 5 LQLWQFLVALLDDP Q9PUQ1 347 347 LQLWQFLVTLLDDP ERM_HUMAN 368 368 LQLWQFLVTLLDDP Q9CXC9 368 368 LQLWQFLVTLLDDP Q9JHB1 368 368 LQLWQFLVTLLDDP Q9PUQ2 380 380 IYLWEFLLALLQDK ELF1_HUMAN 208 208 IYLWEFLLALLQDK ELF1_MOUSE 208 208 IYLWEFLLALLQDK Q9EQY1 116 116 IYLWEFLLALLQDK Q9EQY2 171 171 IYLWEFLLALLQDK Q9EQY3 207 207 ITLWQFLLELLQQD Q27378 64 64 IYLWEFLLALLQDK Q9YH25 201 201 VQLWQFLLEILTDC ELG_DROME 346 346 LQLWQFLVALLDEP Q9VC38 471 471 IYLWEFLLALLQDR O60435 209 209 IYLWEFLLALLQDR Q99607 209 209 IYLWEFLLALLQDR Q9Z2U4 208 208 TYLWEFLLDLLQDK Q15723 196 196 TYLWEFLLDLLQDK Q15724 148 148 TYLWEFLLDLLQDK Q15725 136 136 TYLWEFLLDLLQDK Q9JHC7 148 148 TYLWEFLLDLLQDK Q9JHC8 136 136 TYLWEFLLDLLQDK Q9JHC9 208 208 TYLWEFLLDLLQDK Q9JHD0 196 196 TYLWEFLLDLLQDK Q9YH24 102 102 IQMWQFLLELLTDK Q9YHU5 308 308 TYLWEFLLKLLQDR E74A_DROME 733 733 TYLWEFLLKLLQDR E74B_DROME 787 787 TYLWEFLLRLLQDD O17057 338 338 IQLWHFILELLQKE Q9BX30 35 35 IQLWHFILELLQKE Q9QZW1 35 35 IQLWQFLLELLQDG ETV2_MOUSE 234 234 IQLWHFILELLRKE ERF_HUMAN 27 27 IQLWHFILELLRKE ERF_MOUSE 27 27 IQLWQFLLELLHDG ETV2_HUMAN 240 240 RLLWDFLQQLLNDR O96416 409 409 RLLWDFLQQLLNDR POK_DROME 396 396 IQLWQFLKELLLQP O97145 277 277 THLWEFIRDILLSP O70273 207 207 THLWEFIRDILLSP Q99K12 192 192 THLWEFIRDILLNP Q9H509 184 184 THLWEFIRDILLNP Q9NZC4 207 207 THLWEFIRDILLNP Q9UKF9 207 207 THLWEFIRDILLNP Q9Y5V4 207 207 THLWEFIRDILLNP Q9Y5V5 184 184 IHLWQFLKELLLKP O95238 249 249 IHLWQFLKELLLKP Q9WTP3 239 239 DQGSPFAQELLDDG O35275 160 160 DQGSPFAQELLDDG P78545 160 160 DQGSPFAQELLDDV Q99718 160 160 IHLWQFLKELLASP ETS4_DROME 416 416 SHLWEFVRDLLLSP O95175 163 163 SHLWEFVRDLLLSP Q9Z2K6 161 161 SHLWEFVRDLLLSP Q9UKW5 163 163 SHLWEFVRDLLLSP Q9UKW6 173 173 IRLYQFLLDLLRSG O42415 157 157 IRLYQFLLDLLRSG PU1_HUMAN 164 164 IRLYQFLLDLLRSG PU1_MOUSE 166 166 IRLYQFLLDLLRSG Q99L57 172 172 IRLYQFLLDLLRNG Q9I8M7 167 167 RLLWDYVYQLLSDS ETV6_HUMAN 339 339 RLLWDYVYQLLSDS ETV6_MOUSE 335 335 VHLWQFIRELLDQP Q19695 444 444 IRLYQFLLDLLRNG Q9I8M4 166 166 RLLWDYVYQLLLDT TEL2_HUMAN 224 224 IRLYQFLLDLLRSG Q9DEW6 179 179 LRLLSFLRDLLEDE O01521 44 44 LRLYQFLLGLLTRG O97553 298 298 LRLYQFLLGLLTRG SPIB_HUMAN 169 169 LRLYQFLLGLLQRG Q9I8M6 169 169 VRLYQFLLELLKNG Q9DEW5 173 173 VRLYKFLLELLLNG Q9I8M5 173 173 TRLYQFLMEILQDQ Q9I8M8 201 201 LRLYEFLSESLRDS Q9DEW4 114 114 DQLDQFWSELSSKA P93750 36 36 ETSDOMAIN2 Length of motif = 19 Motif number = 2 ETS domain motif II - 6 PCODE ST INT DGWEFKLTDPDEVARRWGI PNT1_DROME 539 10 DGWEFKLTDPDEVARRWGI PNT2_DROME 634 10 DGWEFKLTDPDEVARRWGI Q9VCN2 634 10 DGWEFKLSDPDEVARRWGK ET1A_XENLA 356 10 DGWEFKLSDPDEVARRWGK ETS1_HUMAN 359 10 DGWEFKLSDPDEVARRWGK ETS1_MOUSE 359 10 DGWEFKLSDPDEVARRWGK ETS1_RAT 359 10 DGWEFKLSDPDEVARRWGK ETSA_CHICK 359 10 DGWEFKLSDPDEVARRWGK ETSB_CHICK 403 10 DGWEFKLSDPDEVARRWGK Q26645 472 10 DGWEFKLTDPDEVARRWGK ET2A_XENLA 390 10 DGWEFKLADPDEVARRWGK ETS2_HUMAN 387 10 DGWEFKLADPDEVARRWGK ETS2_MOUSE 386 10 DGWEFKLADPDEVARRWGK Q99K36 386 10 DGWEFKLADPDEVARRWGK ET2B_XENLA 390 10 TNGEFKLTDPDEVARRWGE ETS3_DROME 35 10 DGWEFKLADPDEVARRWGR ETS2_CHICK 397 10 TNGEFKMTDPDEVARRWGQ Q9BZD1 329 10 TNGEFKMTDPDEVARRWGE ERG_CHICK 334 10 TNGEFKMTDPDEVARRWGE ERG_HUMAN 318 10 TNGEFKMTDPDEVARRWGE FLI1_HUMAN 305 10 TNGEFKMTDPDEVARRWGE FLI1_MOUSE 305 10 TNGEFKMTDPDEVARRWGE O93425 285 10 TNGEFKMTDPDEVARRWGE Q9PU61 304 10 TNGEFKMTDPDEVARRWGE Q9W6Z9 312 10 TNGEFKMTDPDEVARRWGE Q9W700 341 10 GHGEFKLTDPDEVARRWGE O70132 174 10 GHGEFKLTDPDEVARRWGE Q99581 71 10 SNGEFKLVDPDEVARKWGE Q18579 59 10 TQGEFKLVDPDEVARKWGE Q22355 238 10 TNGEFKMTDPDEVARRWGE FLI1_XENLA 306 10 QSGEFRLIDPDEVARRWGE ETS6_DROME 279 10 EDGEFKLLQAEEVARLWGV O57566 40 10 EDGEFKLLQAEEVARLWGG Q9PU63 29 10 NNGEFKLLQAEEVARLWGI ELK4_MOUSE 29 10 EEGEFKLNQPELVAQKWGQ Q9I9E8 334 10 DEGEFKLNQPELVAQKWGQ GABA_HUMAN 344 10 DEGEFKLNQPELVAQKWGQ GABA_MOUSE 344 10 NDGEFKLLQAEEVARLWGV Q98SI4 29 10 RGMEFKLIEPEEVARLWGI ETV4_MOUSE 436 10 NDGEFKLLKAEEVAKLWGL ELK3_HUMAN 29 10 DGGEFKLVDAEEVARLWGL ELK1_HUMAN 30 11 DGGEFKLVDAEEVARLWGL ELK1_MOUSE 30 11 RGMEFKLIEPEEVARRWGI ETV1_HUMAN 359 10 RGMEFKLIEPEEVARRWGI ETV1_MOUSE 359 10 RGMEFKLIEPEEVARRWGI Q9W696 359 10 RGMEFKLIEPEEVARRWGI Q9YHW6 359 10 RGMEFKLIEPEEVARLWGI O57586 374 10 NDGQFKLLQAEEVARLWGI ELK4_HUMAN 29 10 NDGEFKLLKAEEVAKLWGL ELK3_MOUSE 29 10 RGMEFKLIEPEEVARLWGM Q9PUQ1 371 10 RGMEFKLIEPEEVARRWGI ERM_HUMAN 392 10 RGMEFKLIEPEEVARRWGI Q9CXC9 392 10 RGMEFKLIEPEEVARRWGI Q9JHB1 392 10 RGLEFKLIEPEEVARRWGI Q9PUQ2 404 10 EKGIFKLVDSKAVSRLWGK ELF1_HUMAN 234 12 EKGIFKLVDSKAVSRLWGK ELF1_MOUSE 234 12 EKGIFKLVDSKAVSRLWGK Q9EQY1 142 12 EKGIFKLVDSKAVSRLWGK Q9EQY2 197 12 EKGIFKLVDSKAVSRLWGK Q9EQY3 233 12 TDGEFRLIDAEAVARKWGQ Q27378 89 11 EKGIFKLVDSKAVSKLWGK Q9YH25 227 12 TEGEFKLTDPDRVARLWGE ELG_DROME 370 10 RGMEFKLIEPEEVARRWGL Q9VC38 496 11 EKGIFKLVDSKAVSKLWGK O60435 235 12 EKGIFKLVDSKAVSKLWGK Q99607 235 12 EKGIFKLVDSKAVSKLWGK Q9Z2U4 234 12 EKGIFKLVDSKAVSKLWGK Q15723 222 12 EKGIFKLVDSKAVSKLWGK Q15724 174 12 EKGIFKLVDSKAVSKLWGK Q15725 162 12 EKGIFKLVDSKAVSKLWGK Q9JHC7 174 12 EKGIFKLVDSKAVSKLWGK Q9JHC8 162 12 EKGIFKLVDSKAVSKLWGK Q9JHC9 234 12 EKGIFKLVDSKAVSKLWGK Q9JHD0 222 12 EKGIFKLVDSKAVSKLWGK Q9YH24 128 12 EEGEFKLNQPELVAQKWGQ Q9YHU5 332 10 EKGVFKLVDSKAVSRLWGM E74A_DROME 759 12 EKGVFKLVDSKAVSRLWGM E74B_DROME 813 12 AKGIFKLVDSKAVSRLWGM O17057 364 12 EYGEFVIKDPDEVARLWGR Q9BX30 60 11 EYGEFVIKDPDEVARLWGR Q9QZW1 60 11 NSREFQLCDPKEVARLWGE ETV2_MOUSE 258 10 DYGEFVIKDPDEVARLWGV ERF_HUMAN 51 10 DYGEFVIKDPDEVARLWGV ERF_MOUSE 51 10 NSREFQLCDPKEVARLWGE ETV2_HUMAN 264 10 DTGVFKIVDPAGLAKLWGI O96416 436 13 DTGVFKIVDPAGLAKLWGI POK_DROME 423 13 TQGIFKIEDSVEVARLWGL O97145 303 12 SEGIFRFLKSEAVAQLWGK O70273 233 12 SEGIFRFLKSEAVAQLWGK Q99K12 218 12 SEGVFRFLKSEAVAQLWGK Q9H509 210 12 SEGVFRFLKSEAVAQLWGK Q9NZC4 233 12 SEGVFRFLKSEAVAQLWGK Q9UKF9 233 12 SEGVFRFLKSEAVAQLWGK Q9Y5V4 233 12 SEGVFRFLKSEAVAQLWGK Q9Y5V5 210 12 EKGIFKIEDSAQVARLWGI O95238 275 12 EKGIFKIEDSAQVARLWGV Q9WTP3 265 12 HEGVFKFLRSEAVAQLWGQ O35275 299 125 HEGVFKFLRSEAVAQLWGQ P78545 299 125 HEGVFKFLRSEAVAQLWGQ Q99718 276 102 SKGIFKIEDSVRVAKLWGR ETS4_DROME 442 12 EQGIFRVVKSEALAKMWGQ O95175 189 12 EQGIFRVVKSEALAKMWGQ Q9Z2K6 187 12 EQGIFRVVKSEALAKMWGQ Q9UKW5 189 12 EQGIFRVVKSEALAKMWGQ Q9UKW6 199 12 GTFQFSSKHKEALAHRWGI O42415 184 13 GTFQFSSKHKEALAHRWGI PU1_HUMAN 191 13 GTFQFSSKHKEALAHRWGI PU1_MOUSE 193 13 GTFQFSSKHKEALAHRWGI Q99L57 199 13 GTFQFSSKHKEALANRWGI Q9I8M7 194 13 ESKIFRIVDPNGLARLWGN ETV6_HUMAN 364 11 ESKIFRIVDPNGLARLWGN ETV6_MOUSE 360 11 DEGTFKIESSLLLARYWGQ Q19695 470 12 GTFQFSSKHKEALAHRWGI Q9I8M4 193 13 DAKIFRVVDPNGLARLWGN TEL2_HUMAN 249 11 GTFQFSSKHKEVLAHRWGV Q9DEW6 206 13 SESVFKMSKPHKVAELWGA O01521 69 11 GVFQFSSKHKELLARRWGQ O97553 325 13 GVFQFSSKHKELLARRWGQ SPIB_HUMAN 196 13 GVFQFSSKHKEALAHRWGQ Q9I8M6 196 13 GTFQFSSKHKEMLAHRWGM Q9DEW5 200 13 GTFQFSSKHKELLAHRWGQ Q9I8M5 200 13 GIFQFSSQHKEELAKKWGQ Q9I8M8 228 13 GVFQFISKNKEKVAEMWGR Q9DEW4 141 13 DILEFKYVGNDRSARVNGL P93750 322 272 ETSDOMAIN3 Length of motif = 19 Motif number = 3 ETS domain motif III - 6 PCODE ST INT RKNKPKMNYEKLSRGLRYY PNT1_DROME 558 0 RKNKPKMNYEKLSRGLRYY PNT2_DROME 653 0 RKNKPKMNYEKLSRGLRYY Q9VCN2 653 0 RKNKPKMNYEKLSRGLRYY ET1A_XENLA 375 0 RKNKPKMNYEKLSRGLRYY ETS1_HUMAN 378 0 RKNKPKMNYEKLSRGLRYY ETS1_MOUSE 378 0 RKNKPKMNYEKLSRGLRYY ETS1_RAT 378 0 RKNKPKMNYEKLSRGLRYY ETSA_CHICK 378 0 RKNKPKMNYEKLSRGLRYY ETSB_CHICK 422 0 RKNKPKMNYEKLSRGLRYY Q26645 491 0 RKNKPKMNYEKLSRGLRYY ET2A_XENLA 409 0 RKNKPKMNYEKLSRGLRYY ETS2_HUMAN 406 0 RKNKPKMNYEKLSRGLRYY ETS2_MOUSE 405 0 RKNKPKMNYEKLSRGLRYY Q99K36 405 0 RKNKPKMNYEKLSRGLRYY ET2B_XENLA 409 0 RKSKPNMNYDKLSRALRYY ETS3_DROME 54 0 RKNKPKMNYEKLSRGLRYY ETS2_CHICK 416 0 RKSKPNMNYDKLSRALRYY Q9BZD1 348 0 RKSKPNMNYDKLSRALRYY ERG_CHICK 353 0 RKSKPNMNYDKLSRALRYY ERG_HUMAN 337 0 RKSKPNMNYDKLSRALRYY FLI1_HUMAN 324 0 RKSKPNMNYDKLSRALRYY FLI1_MOUSE 324 0 RKSKPNMNYDKLSRALRYY O93425 304 0 RKSKPNMNYDKLSRALRYY Q9PU61 323 0 RKSKPNMNYDKLSRALRYY Q9W6Z9 331 0 RKSKPNMNYDKLSRALRYY Q9W700 360 0 RKSKPNMNYDKLSRALRYY O70132 193 0 RKSKPNMNYDKLSRALRYY Q99581 90 0 RKSKPNMNYDKLSRALRYY Q18579 78 0 RKSKPNMNYDKMSRALRYY Q22355 257 0 RKSKPNMNYDKLSRALRYY FLI1_XENLA 325 0 RKAKPNMNYDKLSRALRYY ETS6_DROME 298 0 RKNKPSMNYDKLSRALRYY O57566 59 0 RKNKPSMNYDKLSRALRYY Q9PU63 48 0 RKNKPNMNYDKLSRALRYY ELK4_MOUSE 48 0 RKNKPTMNYEKLSRALRYY Q9I9E8 353 0 RKNKPTMNYEKLSRALRYY GABA_HUMAN 363 0 RKNKPTMNYEKLSRALRYY GABA_MOUSE 363 0 RKNKPSMNYDKLSRALRYY Q98SI4 48 0 QKNRPAMNYDKLSRSLRYY ETV4_MOUSE 455 0 RKNKTNMNYDKLSRALRYY ELK3_HUMAN 48 0 RKNKTNMNYDKLSRALRYY ELK1_HUMAN 49 0 RKNKTNMNYDKLSRALRYY ELK1_MOUSE 49 0 QKNRPAMNYDKLSRSLRYY ETV1_HUMAN 378 0 QKNRPAMNYDKLSRSLRYY ETV1_MOUSE 378 0 QKNRPAMNYDKLSRSLRYY Q9W696 378 0 QKNRPAMNYDKLSRSLRYY Q9YHW6 378 0 EKNRPAMNYDKLSRSLRYY O57586 393 0 RKNKPNMNYDKLSRALRYY ELK4_HUMAN 48 0 RKNKTNMNYDKLSRALRYY ELK3_MOUSE 48 0 QKNRPAMNYDKLSRSLRYY Q9PUQ1 390 0 QKNRPAMNYDKLSRSLRYY ERM_HUMAN 411 0 QKNRPAMNYDKLSRSLRYY Q9CXC9 411 0 QKNRPAMNYDKLSRSLRYY Q9JHB1 411 0 QKNRPAMNYAKLSRSLRYY Q9PUQ2 423 0 HKNKPDMNYETMGRALRYY ELF1_HUMAN 253 0 HKNKPDMNYETMGRALRYY ELF1_MOUSE 253 0 HKNKPDMNYETMGRALRYY Q9EQY1 161 0 HKNKPDMNYETMGRALRYY Q9EQY2 216 0 HKNKPDMNYETMGRALRYY Q9EQY3 252 0 RKAKPHMNYDKLSRALRYY Q27378 108 0 HKNKPDMNYETMGRALRYY Q9YH25 246 0 KKNKPAMNYEKLSRALRYY ELG_DROME 389 0 QKNRPAMNYDKLSRSLRYY Q9VC38 515 0 QKNKPDMNYETMGRALRYY O60435 254 0 QKNKPDMNYETMGRALRYY Q99607 254 0 QKNKPDMNYETMGRALRYY Q9Z2U4 253 0 HKNKPDMNYETMGRALRYY Q15723 241 0 HKNKPDMNYETMGRALRYY Q15724 193 0 HKNKPDMNYETMGRALRYY Q15725 181 0 HKNKPDMNYETMGRALRYY Q9JHC7 193 0 HKNKPDMNYETMGRALRYY Q9JHC8 181 0 HKNKPDMNYETMGRALRYY Q9JHC9 253 0 HKNKPDMNYETMGRALRYY Q9JHD0 241 0 HKNKPDMNYETMGRALRYY Q9YH24 147 0 RKNKPTMNYEKLSRALRYY Q9YHU5 351 0 HKNKPDMNYETMGRALRYY E74A_DROME 778 0 HKNKPDMNYETMGRALRYY E74B_DROME 832 0 HKNKPGMNYETMGRALRYY O17057 383 0 RKCKPQMNYDKLSRALRYY Q9BX30 79 0 RKCKPQMNYDKLSRALRYY Q9QZW1 79 0 RKRKPGMNYEKLSRGLRYY ETV2_MOUSE 277 0 RKCKPQMNYDKLSRALRYY ERF_HUMAN 70 0 RKCKPQMNYDKLSRALRYY ERF_MOUSE 70 0 RKRKPGMNYEKLSRGLRYY ETV2_HUMAN 283 0 QKNHLSMNYDKMSRALRYY O96416 455 0 QKNHLSMNYDKMSRALRYY POK_DROME 442 0 RKNRPAMNYDKLSRSIRQY O97145 322 0 KKNNSSMTYEKLSRAMRYY O70273 252 0 KKNNSSMTYEKLSRAMRYY Q99K12 237 0 KKNNSSMTYEKLSRAMRYY Q9H509 229 0 KKNNSSMTYEKLSRAMRYY Q9NZC4 252 0 KKNNSSMTYEKLSRAMRYY Q9UKF9 252 0 KKNNSSMTYEKLSRAMRYY Q9Y5V4 252 0 KKNNSSMTYEKLSRAMRYY Q9Y5V5 229 0 RKNRPAMNYDKLSRSIRQY O95238 294 0 RKNRPAMNYDKLSRSIRQY Q9WTP3 284 0 KKKNSNMTYEKLSRAMRYY O35275 318 0 KKKNSNMTYEKLSRAMRYY P78545 318 0 KKKNSNMTYEKLSRAMRYY Q99718 295 0 RKNRPAMNYDKLSRSIRQY ETS4_DROME 461 0 RKKNDRMTYEKLSRALRYY O95175 208 0 RKKNDRMTYEKLSRALRYY Q9Z2K6 206 0 RKKNDRMTYEKLSRALRYY Q9UKW5 208 0 RKKNDRMTYEKLSRALRYY Q9UKW6 218 0 KGNRKKMTYQKMARALRNY O42415 204 1 KGNRKKMTYQKMARALRNY PU1_HUMAN 211 1 KGNRKKMTYQKMARALRNY PU1_MOUSE 213 1 KGNRKKMTYQKMARALRNY Q99L57 219 1 KGNRKKMTYQKMARALRNY Q9I8M7 214 1 HKNRTNMTYEKMSRALRHY ETV6_HUMAN 383 0 HKNRTNMTYEKMSRALRHY ETV6_MOUSE 379 0 RKNRSQMNYDKLSRSLRQY Q19695 489 0 KGNRKKMTCQKMARALRNY Q9I8M4 213 1 HKNRVNMTYEKMSRALRHY TEL2_HUMAN 268 0 KGNRKKMTYQKMARALRNY Q9DEW6 226 1 ATGNPGMNYDKMSRGLRYF O01521 88 0 KGNRKRMTYQKLARALRNY O97553 345 1 KGNRKRMTYQKLARALRNY SPIB_HUMAN 216 1 KGNRKAMTYQKMARALRNY Q9I8M6 216 1 KGNRKKMTYQKMARALRNY Q9DEW5 220 1 KGNRKKMTYQKMARALRNY Q9I8M5 220 1 KGNRKAMTYQKLARALRNY Q9I8M8 248 1 KGNRKTMTYQKMARALRNY Q9DEW4 161 1 FKSDSDLDVSKLNRANRYT P93750 759 418 ETSDOMAIN4 Length of motif = 19 Motif number = 4 ETS domain motif IV - 6 PCODE ST INT YDKNIIHKTAGKRYVYRFV PNT1_DROME 577 0 YDKNIIHKTAGKRYVYRFV PNT2_DROME 672 0 YDKNIIHKTAGKRYVYRFV Q9VCN2 672 0 YDKNIIHKTAGKRYVYRFV ET1A_XENLA 394 0 YDKNIIHKTAGKRYVYRFV ETS1_HUMAN 397 0 YDKNIIHKTAGKRYVYRFV ETS1_MOUSE 397 0 YDKNIIHKTAGKRYVYRFV ETS1_RAT 397 0 YDKNIIHKTAGKRYVYRFV ETSA_CHICK 397 0 YDKNIIHKTAGKRYVYRFV ETSB_CHICK 441 0 YDKNIIHKTAGKRYVYRFV Q26645 510 0 YDKNIIHKTSGKRYVYRFV ET2A_XENLA 428 0 YDKNIIHKTSGKRYVYRFV ETS2_HUMAN 425 0 YDKNIIHKTSGKRYVYRFV ETS2_MOUSE 424 0 YDKNIIHKTSGKRYVYRFV Q99K36 424 0 YDKNIIHKTSGKRYVYRFV ET2B_XENLA 428 0 YDKNIMTKVHGKRYAYKFD ETS3_DROME 73 0 YDKNIIHKTSGKRYVYRFV ETS2_CHICK 435 0 YDKNIMTKVHGKRYAYKFD Q9BZD1 367 0 YDKNIMTKVHGKRYAYKFD ERG_CHICK 372 0 YDKNIMTKVHGKRYAYKFD ERG_HUMAN 356 0 YDKNIMTKVHGKRYAYKFD FLI1_HUMAN 343 0 YDKNIMTKVHGKRYAYKFD FLI1_MOUSE 343 0 YDKNIMTKVHGKRYAYKFD O93425 323 0 YDKNIMTKVHGKRYAYKFD Q9PU61 342 0 YDKNIMTKVHGKRYAYKFD Q9W6Z9 350 0 YDKNIMTKVHGKRYAYKFD Q9W700 379 0 YDKNIMSKVHGKRYAYRFD O70132 212 0 YDKNIMSKVHGKRYAYRFD Q99581 109 0 YDKNIMTKVQGKRYAYKFD Q18579 97 0 YDKNIMAKVHGKRYAYKFD Q22355 276 0 YDKSIMTKVHGKRYAYKFD FLI1_XENLA 344 0 YDKNIMTKVHGKRYAYKFD ETS6_DROME 317 0 YDKNIIKKVNGQKFVYRFV O57566 78 0 YDKNIIKKVNGQKFVYRFV Q9PU63 67 0 YVKNIIKKVNGQKFVYKFV ELK4_MOUSE 67 0 YDGDMISKVQGKRFVYKFV Q9I9E8 372 0 YDGDMICKVQGKRFVYKFV GABA_HUMAN 382 0 YDGDMICKVQGKRFVYKFV GABA_MOUSE 382 0 YVKNIIKKVNGQKFVYKFV Q98SI4 67 0 YEKGIMQKVAGERYVYKFV ETV4_MOUSE 474 0 YDKNIIKKVIGQKFVYKFV ELK3_HUMAN 67 0 YDKNIIRKVSGQKFVYKFV ELK1_HUMAN 68 0 YDKNIIRKVSGQKFVYKFV ELK1_MOUSE 68 0 YEKGIMQKVAGERYVYKFV ETV1_HUMAN 397 0 YEKGIMQKVAGERYVYKFV ETV1_MOUSE 397 0 YEKGIMQKVAGERYVYKFV Q9W696 397 0 YEKGIMQKVAGERYVYKFV Q9YHW6 397 0 YEKGIMQKVAGERYVYKFV O57586 412 0 YVKNIIKKVNGQKFVYKFV ELK4_HUMAN 67 0 YDKNIIKKVIGQKFVYKFV ELK3_MOUSE 67 0 YEKGIMQKVAGERYVYKFV Q9PUQ1 409 0 YEKGIMQKVAGERYVYKFV ERM_HUMAN 430 0 YEKGIMQKVAGERYVYKFV Q9CXC9 430 0 YEKGIMQKVAGERYVYKFV Q9JHB1 430 0 YEKGIMQKVAGERYVYKFV Q9PUQ2 442 0 YQRGILAKVEGQRLVYQFK ELF1_HUMAN 272 0 YQRGILAKVEGQRLVYQFK ELF1_MOUSE 272 0 YQRGILAKVEGQRLVYQFK Q9EQY1 180 0 YQRGILAKVEGQRLVYQFK Q9EQY2 235 0 YQRGILAKVEGQRLVYQFK Q9EQY3 271 0 YEKNIIKKVIGKKFVYRFV Q27378 127 0 YQRGILAKVEGQRLVYQFK Q9YH25 265 0 YDGDMISKVSGKRFAYKFD ELG_DROME 408 0 YEKGIMQKVNGERYVYRFV Q9VC38 534 0 YQRGILAKVEGQRLVYQFK O60435 273 0 YQRGILAKVEGQRLVYQFK Q99607 273 0 YQRGILAKVEGQRLVYQFK Q9Z2U4 272 0 YQRGILAKVEGQRLVYQFK Q15723 260 0 YQRGILAKVEGQRLVYQFK Q15724 212 0 YQRGILAKVEGQRLVYQFK Q15725 200 0 YQRGILAKVEGQRLVYQFK Q9JHC7 212 0 YQRGILAKVEGQRLVYQFK Q9JHC8 200 0 YQRGILAKVEGQRLVYQFK Q9JHC9 272 0 YQRGILAKVEGQRLVYQFK Q9JHD0 260 0 YQRGILAKVEGQRLVYQFK Q9YH24 166 0 YDGDMISKVQGKRFVNKFV Q9YHU5 370 0 YQRGILAKVDGQRLVYHFV E74A_DROME 797 0 YQRGILAKVDGQRLVYHFV E74B_DROME 851 0 YQRGILQKVDGQRLVYRFV O17057 402 0 YNKRILHKTKGKRFTYKFN Q9BX30 98 0 YNKRILHKTKGKRFTYKFN Q9QZW1 98 0 YRRDIVLKSGGRKYTYRFG ETV2_MOUSE 296 0 YNKRILHKTKGKRFTYKFN ERF_HUMAN 89 0 YNKRILHKTKGKRFTYKFN ERF_MOUSE 89 0 YRRDIVRKSGGRKYTYRFG ETV2_HUMAN 302 0 YRVNILRKVQGERHCYQFL O96416 474 0 YRVNILRKVQGERHCYQFL POK_DROME 461 0 YRKGIMKKTEVSQRLVYQF O97145 341 0 YKREILERVDGRRLVYKFG O70273 271 0 YKREILERVDGRRLVYKFG Q99K12 256 0 YKREILERVDGRRLVYKFG Q9H509 248 0 YKREILERVDGRRLVYKFG Q9NZC4 271 0 YKREILERVDGRRLVYKFG Q9UKF9 271 0 YKREILERVDGRRLVYKFG Q9Y5V4 271 0 YKREILERVDGRRLVYKFG Q9Y5V5 248 0 YKKGIIRKPDISQRLVYQF O95238 313 0 YKKGIIRKPDISQRLVYQF Q9WTP3 303 0 YKREILERVDGRRLVYKFG O35275 337 0 YKREILERVDGRRLVYKFG P78545 337 0 YKREILERVDGRRLVYKFG Q99718 314 0 YKKGIMKKTERSQRLVYQF ETS4_DROME 480 0 YYKTGILERVDRRLVYKFG O95175 226 -1 YYKTRILERVDRRLVYKFG Q9Z2K6 224 -1 YYKTGILERVDRRLMYKFG Q9UKW5 226 -1 YYKTGILERVDRRLMYKFG Q9UKW6 236 -1 YGKTGEVKKVKKKLTYQFS O42415 222 -1 YGKTGEVKKVKKKLTYQFS PU1_HUMAN 229 -1 YGKTGEVKKVKKKLTYQFS PU1_MOUSE 231 -1 YGKTGEVKKVKKKLTYQFS Q99L57 237 -1 YGKTGEVKKVKKKLTYQFS Q9I8M7 232 -1 YKLNIIRKEPGQRLLFRFM ETV6_HUMAN 402 0 YKLNIIRKEPGQRLLFRFM ETV6_MOUSE 398 0 YKKGIIQKPEKKQRLVYKF Q19695 508 0 YGKTGEVKKIKKKLTYQFS Q9I8M4 231 -1 YKLNIIKKEPGQKLLFRFL TEL2_HUMAN 287 0 YGKTGEVRKIKKKLTYQFS Q9DEW6 244 -1 YTNNTLEKVPGKDARYRFI O01521 107 0 YAKTGEIRKVKRKLTYQFD O97553 363 -1 YAKTGEIRKVKRKLTYQFD SPIB_HUMAN 234 -1 YGKTGEIRKVKKKLTYQFG Q9I8M6 234 -1 YGKTGEIRKIKKKLTYQFD Q9DEW5 238 -1 YGKTGEIRKVKKKLTYQFD Q9I8M5 238 -1 YEATGEIRKIKKKLTYQFG Q9I8M8 266 -1 YSRTGEIVKVRRKLTYRFD Q9DEW4 179 -1 YRREIRSKMNNSRNACKMD P93750 781 3

User query: Display/Full Code "ETSDOMAIN"